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Research peptides

Mitochondrial Peptides

Mitochondrial peptides are a young research field. The mitochondria are the energy producers of the cell, and some peptides are either produced by them or act directly on their membranes. This category contains the two best known mitochondrial peptides, MOTS-c...

NAD+ 500mgNAD+ 500mg€80,00Longevity SS-31 10mgSS-31 10mg€60,00Mitochondrial MOTS-c 20mgMOTS-c 20mg€95,00Mitochondrial

Mitochondrial peptides are a young research field. The mitochondria are the energy producers of the cell, and some peptides are either produced by them or act directly on their membranes. This category contains the two best known mitochondrial peptides, MOTS-c and SS-31, together with the coenzyme NAD+ as a reference compound.

Mitochondrial peptides in this category

  • MOTS-c 20 mg: a 16 amino acid peptide that is encoded in the mitochondrial DNA itself. It was described in 2015 and is studied in glucose metabolism, insulin sensitivity and exercise physiology.
  • SS-31 10 mg: also called Elamipretide, a four amino acid peptide that binds to cardiolipin in the inner mitochondrial membrane. It has been tested in clinical trials for rare mitochondrial diseases.
  • NAD+ 500 mg: nicotinamide adenine dinucleotide, the coenzyme that carries electrons in the respiratory chain. COA on file.

How MOTS-c and SS-31 differ

MOTS-c works as a signalling molecule. It moves to the cell nucleus under metabolic stress and influences gene expression. SS-31 works structurally. It stabilises the folds of the inner mitochondrial membrane and is studied for its effect on the efficiency of the respiratory chain. NAD+ is the substrate that this chain uses, which makes it a useful control in the same experiments.

MOTS-c also appears in our GLP-1 and weight management category because of its role in metabolic research, and all three compounds are part of our anti-aging and longevity peptides.

Handling of mitochondrial peptides

All compounds are supplied as lyophilised powder in sealed vials. SS-31 and MOTS-c are stored frozen for long-term storage and dissolved in bacteriostatic water before use. Our guide on how to reconstitute peptides explains the steps.

Research status of mitochondrial peptides

SS-31 has been tested in human clinical trials but is not approved as a medicine. MOTS-c has been studied in animals and cell cultures. Both compounds are sold here for laboratory research use only and are not intended for human or veterinary use.